Table 2. Prospective risks of stillbirth and neonatal death for 2 consecutive weeks at term, and the number needed to harm (NNH) for 1 additional stillbirth when pregnancy is continued to the next week.
Gestational age (weeks) | Number of studies | Number of stillbirths | Number of pregnancies | Risk ratio* | 95% CI** | Risk difference* (×1,000) | 95% CI** | NNH*** | 95% CI** |
---|---|---|---|---|---|---|---|---|---|
Stillbirth | |||||||||
37+0–6 | 12 | 3,250 | 8,566,961 | 1.29 | 1.18, 1.40 | 0.11 | 0.07, 0.15 | 9,058 | 6,714, 13,724 |
38+0–6 | 12 | 3,516 | 8,032,865 | 1.32 | 1.22, 1.44 | 0.16 | 0.11, 0.21 | 6,242 | 4,735, 8,839 |
39+0–6 | 12 | 3,620 | 6,784,040 | 1.64 | 1.51, 1.79 | 0.42 | 0.35, 0.50 | 2,367 | 1,997, 2,852 |
40+0–6 | 12 | 3,426 | 4,687,330 | 1.64 | 1.51, 1.77 | 0.69 | 0.57, 0.81 | 1,449 | 1,237, 1,747 |
41+0–6 | 12 | 2,407 | 2,273,471 | 1.94 | 1.72, 2.19 | 1.66 | 1.29, 2.06 | 604 | 486, 775 |
42+0–6 | 12 | 1,335 | 700,610 | 1.93 | 1.50, 2.36 | 3.18 | 1.84, 4.35 | 315 | 230, 543 |
≥43 | 6 | 276 | 82,039 | — | — | — | — | — | — |
Neonatal death | |||||||||
37+0–6 | 5 | 296 | 552,964 | 0.41 | 0.26, 0.57 | −0.52 | −0.76, −0.31 | −1,923 | −3,226, −1,316 |
38+0–6 | 5 | 428 | 1,210,730 | 0.94 | 0.68, 1.49 | −0.02 | −0.14, 0.12 | −50,000 | −7,143, 8,333 |
39+0–6 | 5 | 560 | 2,029,277 | 1.13 | 0.90, 1.50 | 0.05 | −0.04, 0.14 | 20,000 | −25,000, 7,143 |
40+0–6 | 5 | 669 | 2,197,643 | 0.85 | 0.64, 1.13 | −0.06 | −0.15, 0.04 | −16,667 | −6,667, 25,000 |
41+0–6 | 5 | 347 | 1,127,117 | 1.87 | 1.07, 2.86 | 0.28 | 0.02, 0.54 | 3,571 | 1,852, 50,000 |
42+0–6 | 4 | 44 | 70,322 | 1.32 | 0.20, 3.38 | 0.19 | −0.52, 1.22 | 5,263 | −1,923, 820 |
≥43 | 4 | 4 | 6,370 | — | — | — | — | — | — |
*Risk differences and risk ratios refer to the change in the risk of delivering 1 week later as compared to delivering at that age.
**Bootstrap CI 95% (P2.5th, P97.5th).
***Number needed to harm when pregnancy is prolonged to the next week, compared to delivery at that gestation, to experience 1 additional stillbirth or neonatal death.