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. 2019 Jul 2;16(7):e1002847. doi: 10.1371/journal.pmed.1002847

Table 6. Univariate and multivariate Cox regression analysis predicting prostate-cancer-specific mortality in the Validation-TMA series.

Parameter Univariate analysis Multivariate analysis
HR (95% CI) p-Value HR (95% CI) p-Value
pT 3.26 (1.84–5.78) <0.001 1.46 (0.79–2.68) 0.222
RP Gleason score 3.56 (2.43–5.20) <0.001 3.18 (2.13–4.74) <0.001
Benign adjacent tissue
p65 continuous 1.00 (0.89–1.14) 0.937
p65 >3% versus ≤3% 1.32 (0.66–2.64) 0.430
Tumor tissue
p65 continuous 1.02 (0.99–1.06) 0.147
p65 >3% versus ≤3% 3.12 (1.55–6.27) 0.001 2.63 (1.30–5.31) 0.033

Significant p-values given in bold.

95% CI, 95% confidence interval; HR, hazard ratio; pT, pathological staging of the primary tumor; RP, radical prostatectomy.