Table 6. Univariate and multivariate Cox regression analysis predicting prostate-cancer-specific mortality in the Validation-TMA series.
Parameter | Univariate analysis | Multivariate analysis | ||
---|---|---|---|---|
HR (95% CI) | p-Value | HR (95% CI) | p-Value | |
pT | 3.26 (1.84–5.78) | <0.001 | 1.46 (0.79–2.68) | 0.222 |
RP Gleason score | 3.56 (2.43–5.20) | <0.001 | 3.18 (2.13–4.74) | <0.001 |
Benign adjacent tissue | ||||
p65 continuous | 1.00 (0.89–1.14) | 0.937 | ||
p65 >3% versus ≤3% | 1.32 (0.66–2.64) | 0.430 | ||
Tumor tissue | ||||
p65 continuous | 1.02 (0.99–1.06) | 0.147 | ||
p65 >3% versus ≤3% | 3.12 (1.55–6.27) | 0.001 | 2.63 (1.30–5.31) | 0.033 |
Significant p-values given in bold.
95% CI, 95% confidence interval; HR, hazard ratio; pT, pathological staging of the primary tumor; RP, radical prostatectomy.