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. 2019 May 29;44(2):503–512. doi: 10.3892/ijmm.2019.4214

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Copyright: © Li et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Schematic diagram of the signaling pathway in which TMP suppresses H₂O₂-induced damage in PRGCs. TMP ameliorated H₂O₂-induced damage in PRGCs via the miR-182/mitochondria apoptotic pathway. miR, microRNA; PRGC, primary retinal ganglion cell; ROS, reactive oxygen species; TMP, tetramethylpyrazine.