Fig 5. Lifelong mCMV infection results in inflammation in the adipose tissue.
12-week-old C57BL/6J mice were injected with 105 pfu of mCMV and sacrificed at greater than 450d p.i.. Total adipose tissue was homogenized and analyzed by BioLegend LegendPlex. (A) IL-23 (B) IL-1α (C) IFNγ (D) TNFα (E) CCL2 (F) IL-6 (G) IL-27 and (H) GM-CSF were all statistically increased. Data are pooled results of two independent experiments. n = 9 uninfected and 10 infected animals total. Error bars represent mean ± SEM. *p < 0.05; **p < 0.01; ***p < 0.001; **** p ≤ 0.0001 by unpaired two-tailed Mann-Whitney U test.