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. 2019 May 2;151(7):954–966. doi: 10.1085/jgp.201812310

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© 2019 Henriques et al.

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Figure 6. — Lack of Ca²⁺-activated currents in supporting cells from TMEM16A KO mice. (A) Representative whole-cell recordings obtained with pipette solutions containing 0 or 1.5 µM Ca²⁺, as indicated. The voltage protocol is reported at the top of the panel. (B) Scatter dot plot with average ± SEM showing current amplitudes measured at −80 and +80 mV in the presence of the following [Ca²⁺]_i: for WT mice nominally 0 (n = 17), 1.5 µM (n = 33) or for TMEM16A KO mice nominally 0 (n = 10), 1.5 µM (n = 16). ***, P < 0.001, Tukey test after one-way ANOVA. Recordings were obtained from supporting cells located close to the transition zone with the respiratory epithelium.