Figure 5.

Migration and invasion inhibition of bladder cancer cells by the combined treatment of celecoxib and miR-145 mimic. The 5637 and T24 cells were treated with celecoxib (60 µM) at 24 h following transfection with or without miR-NC mimic or miR-145 mimic (20 nM). Migration and invasion of 5637 and T24 cells following the combined treatment of celecoxib and miR-145 mimic were detected by (A) Transwell assays which were (B) quantified and (C) wound healing assays, respectively (magnification ×100). ^*P<0.05 vs. the DMSO and miR-NC mimic group. ^**P<0.05 vs. all other groups. miR, microRNA; NC, negative control; DMSO, dimethyl sulfoxide.