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. 2019 May 23;44(2):617–629. doi: 10.3892/ijmm.2019.4208

Figure 5.

Figure 5

Effect of cDC manipulation on lung edema and lung injury. LWW/BW and the lung injury score were measured to assess lung edema and lung injury at 6 and 24 h post-LPS challenge, respectively. (A) Hematoxylin and eosin staining (magnification, ×200) of lung tissues at 6 h and (B) at 24 h post-LPS challenge. (C) Lung injury score at 6 h and (D) at 24 h post-LPS challenge. (E) LWW/BW at 6 h and (F) at 24 h post-LPS challenge. Lung injury score is expressed as arbitrary mean units. Data are presented as the mean ± standard deviation (n=6). *P<0.05 vs. Control; #P<0.05 vs. ARDS; &P<0.05 vs. FLT3L+ARDS; and $P<0.05 vs. lestaurtinib+ARDS. cDC, classical dendritic cell; LWW/BW, lung wet weight to body weight; LPS, lipopolysaccharide; ARDS, acute respiratory distress syndrome; FLT3L, Fms-like tyrosine kinase 3-ligand.