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. 2019 May 23;44(2):617–629. doi: 10.3892/ijmm.2019.4208

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Copyright: © Li et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Effect of cDC manipulation on Th1/Th2 cytokine production. (A) Levels of IFN-γ, (B) IL-1β, (C) IL-4 and (D) IL-10 were measured in the lungs by ELISA at 24 h post-LPS challenge, in order to evaluate the Th1/Th2 cytokine production. Data are presented as the mean ± standard deviation (n=6). ^*P<0.05 vs. Control; ^#P<0.05 vs. ARDS; ^&P<0.05 vs. FLT3L+ARDS; and ^$P<0.05 vs. lestaurtinib+ARDS. cDC, classical dendritic cell; Th, T helper cell; IFN, interferon; IL, interleukin; LPS, lipopolysaccharide; ARDS, acute respiratory distress syndrome; FLT3L, Fms-like tyrosine kinase 3-ligand.