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. 2019 May 30;216(7):1582–1598. doi: 10.1084/jem.20181895

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© 2019 Hisano et al.

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Figure 10. — LPAR1 regulates transferred lymphocyte trafficking at lymph nodes. (A) CFSE-labeled lymphocytes were injected into mice treated with vehicle or AM095 (30 mg/kg, gavage), and then the number of CD4- and CFSE-positive cells in lymph nodes and spleen was counted. n = 6 for each group; expressed as mean ± SD. P values were determined using an unpaired Student’s t test; *, P ≤ 0.0048. (B) 35-µm lymph node sections from vehicle- or AM095-treated mice were stained with VEGFR3 (white, LECs), B220 (red, B cells), CD8a (blue, T cells), and CFSE-CD4 (green, T cells). Bars, 100 µm. ns, not significant.