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. 2019 Jun 28;11:5745–5756. doi: 10.2147/CMAR.S197455

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© 2019 Xiong et al.

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Mutations of the selected panel of genes in the RTK/RAS/PI(3)K signaling pathway. The HCC patients were classified into a recurrent HCC group and non-recurrent or naïve HCC group. The mutation frequencies of the selected genes in the RTK/RAS/PI(3)K signaling pathway were assessed and compared in all HCC cases, cases of recurrent HCC, and cases of non-recurrent HCC. (A) Frequency of mutations in the genes in the RTK/RAS/PI(3)K pathway. (B) Kaplan–Meier recurrence plot for the mutated group and non-mutated group for the selected genes in RTK/RAS/PI(3)K pathway. (C) Comparison of profiles of the selected genes in the RTK/RAS/PI(3)K pathway between the recurrent and non-recurrent HCC groups.

Abbreviation: HCC, hepatocellular carcinoma.