Table 2.
Immune response before and after varicella vaccination.
| Characteristics | CS1 | CS2 | CS3 | Pooled CS | LPS | P valueb | P valuec | Difference % (95%CI) |
|---|---|---|---|---|---|---|---|---|
| Pre-vaccination | ||||||||
| Seropositive (n) | 83 | 83 | 77 | 243 | 41 | - | - | - |
| Seronegative (n) | 242 | 245 | 246 | 733 | 128 | - | - | - |
| Seropositive rate, % | 25.54 | 25.30 | 23.84 | 24.90 | 24.26 | 0.8633 | 0.8594 | - |
| (95% CI) | (20.89–30.64) | (20.69–30.37) | (19.30–28.87) | (22.21–27.73) | (18.01–31.44) | |||
| GMT (95% CI) | 2.63 (2.48–2.79) | 2.59 (2.45–2.74) | 2.54 (2.41–2.67) | 2.59 (2.51–2.67) | 2.61 (2.40–2.84) | 0.6507 | 0.8380 | - |
| Post-vaccination | ||||||||
| Seroconversion rate, %(95% CI) | 97.54 (95.21–98.93) | 95.73 (92.94–97.65) | 96.90 (94.38–98.51) | 96.72 (95.40–97.75) | 92.90 (87.93–96.28) | 0.4208 | 0.0274 | 3.82 (0.55–8.81) |
| GMT (95% CI) | 25.04 (22.85–27.44) | 24.47 (22.35–26.78) | 25.88 (23.61–28.36) | 25.12 (23.83–26.47) | 23.43 (20.74–26.47) | 0.6928 | 0.3156 | - |
| GMI (95% CI) | 9.51 (8.72–10.37) | 9.43 (8.65–10.29) | 10.20 (9.36–11.10) | 9.70 (9.23–10.20) | 8.97 (7.93–10.15) | 0.3891 | 0.2372 | - |
bThe P values were calculated for comparisons of the three consecutive CS groups and LPS group by ANOVA.
cThe P values were calculated for comparison of the pooled CS group and LPS group by Fisher’ exact test.