. 2019 Jul 2;14(7):e0219158. doi: 10.1371/journal.pone.0219158

Table 5. Physical performance during the perioperative period within and between the intervention (n = 10) and standard care (n = 11) group.

	Intervention group						Standard care group						Between groups
	Baseline	Pre-surgery	Change		Post-surgery		Baseline	Pre-surgery	Change		Post-surgery		Change from baseline to pre- surgery
Variables	Median (95% CI)			p^§^,^a		p^§^,^b	Median (95% CI)			p^§^,^a		p^§^,^b	ES (95% CI)
Walking distance, meters	418.5	398	15	NS	330	0.03	432	426	-4	NS	278.5	0.003	0.64
Walking distance, meters	(300; 531)	(279; 553)	(-29; 46)		(241; 448)^†		(357; 476)	(380; 482)	(-16; 20)		(115; 402)^††		(0.35; 0.93)
Functional leg strength, n	11	13.5	+3.5	NS	11	NS	11	12	+1	NS	11.5	0.02	0.68
Functional leg strength, n	(6; 14)	(10; 16)	(0; 4)		(1; 13)^†		(8; 15)	(9; 16)	(-0.3; 3.3)		(4; 14)^††		(0.41; 0.94)
Gait speed, m/s
Habitual	1.04	1.15	+0.09	NS	0.89	0.01	1.06	1.12	+0.09	NS	0.80	NS	0.56
Habitual	(0.86; 1.25)	(0.91; 1.53)	(0; 0.3)		(0.71; 1.24)^†		(0.86; 1.22)	(0.94; 1.26)	(-0.002; 0.13)		(0.60; 1.08)^††		(0.25; 0.86)
Maximal	1.57	1.57	-0.02	NS	1.15	NS	1.67	1.56	0	NS	1.28	0.04	0.32
Maximal	(1.11; 1.91)	(1.01; 1.91)	(-0.1; 0.03)		(0.94; 1.50)^†		(1.20; 1.89)	(1.29; 2.05)	(-0.1; 0.3)		(0.73; 1.44)^††		(0.06; 0.59)
MIP, cmH₂O	63.5	78	+17	0.01	79	NS	61	62	-2	NS	44	NS	0.90
MIP, cmH₂O	(37; 90)	(60; 111)	(7; 25)		(56; 89)^†		(44; 89)	(44; 97)	(-6; 4)		(23; 79)^†		(0.71; 1.08)^*

Abbreviations: CI = Confidence Interval, MIP = Maximal Inspiratory Pressure, ES = Effect size (Probabilistic Index based on Mann Whitney U test [48]).

^† n = 9

^†† n = 8

^§ = Bonferroni-corrected p-value from pairwise comparison if the Friedmans ANOVA was statistically significant

^a = Between baseline and pre-surgery

^b = Between pre-surgery and post-surgery

NS = Not statistically significant

* p<0.01 (Mann Whitney U test)