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. 2019 Apr 30;11(4):e4573. doi: 10.7759/cureus.4573

Table 1. Statistical analysis of variables with respect to patients undergoing emergency cholecystectomy.

Demographic, clinical and pathological factors   Standard cholecystectomy Difficult cholecystectomy Uni-variate analysis Multi-variate analysis Risk ratio (Confidence Interval)
(n = 28) (n = 121)
Age   > 60 years 3 (10.7%) 43 (35.5%) 0.012 0.238 2.112 (0.611-7.302)
Gender Female 23 (82.1%) 83 (68.6%) 0.173    
Co-morbidities Cardiac   3 (10.7%)   24 (19.8%)   0.413    
  Respiratory 1 (3.6%) 13 (10.7%) 0.470    
Frailty score >0 10 (35.7%) 60 (49.6%) 0.161    
Diagnosis   Biliary Colic 9 (32.1%) 15 (12.4%) 0.010 0.150 1.889 (0.794-4.493)
  Cholecystitis 11 (39.3%) 75 (62.0%)      
  Pancreatitis 8 (28.6%) 28 (23.1%)      
  Cholangitis 0 (0%) 3 (2.5%)      
Ultra Sound Findings    Thick walled Gall Bladder   11 (39.3%)   64 (52.9%)   0.167    
  CBD dilated 5 (17.9%) 22 (18.1%) 1.000    
ERCP Pre Surgery 0 (0%) 15 (12.4%) 0.075    
Pre-surgery physiology   HR >90 2 (7.1%) 32 (26.4%) 0.027 0.345 2.055 (0.461-9.150)
  Systolic BP <110 / >130 9 (32.1%) 48 (39.7%) 0.523    
Admission to cholecystectomy >3 days 11 (39.3%) 60 (49.6%) 0.325    
Elevated pre-operative blood tests Bilirubin 5 (17.9%) 32 (26.4%) 0.468    
  Alkaline phosphatase 12 (42.9%) 74 (61.2%) 0.089    
  Alanine transaminase 13 (46.4%) 69 (57.0%) 0.289    
  White cell count 8 (28.6%) 48 (39.7%) 0.387    
  CRP >100 2 (7.1%) 53 (43.8%) <0.001 0.041 4.919 (1.066-22.704)
Post-operative Complications 3 (10.7%) 20 (16.5%) 0.440    
  Re-admissions 4 (14.3%) 12 (9.9%) 0.500