Figure 4.

Inhibition of UVB-induced histological alteration by FRB, FSB and FSC in hairless mice. Histological alterations of epidermal thickness, collagen degradation and mast cell infiltration were analyzed using (A) haemotoxylin and eosin staining, (B) epidermal thickness of dorsal skin, (C) Masson's trichrome staining and (D) toluidine blue staining, respectively. All values are presented as the mean ± standard deviation. A Kruskal-Wallis nonparametric test and Bonferroni's post-hoc tests were used to control for multiple comparisons. ^bP<0.01 vs. normal control mice. FRB, fermented rice bran; FSB, fermented soybean cake; FSC, fermented sesame seed cake; UVB, ultraviolet B; RA, retinoic acid.