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. 2019 Mar 22;20(6):750–759. doi: 10.1080/15384047.2018.1564560

Figure 5.

Figure 5.

Downregulated HMGA2 blocked HNSCC cell cycle and suppressed cell migration. (a–b) Cell cycle phase was observed under a flow cytometer. On transfection with si-HMGA2, more SCC-25 and FaDu cells were detected in G0/G1 phase in comparison with the NC condition. (c) Pictures of wound healing assay results illustrated retarded wound-healing progress in SCC-25 and FaDu cells transfected with si-HMGA2. (d) Bar charts plotted results from wound healing assay. Downregulation of HMGA2 resulted in significantly shorter cell migration distance. *, P < 0.05, **, P < 0.01 compared with NC group. Scale bar: 200 μm.