Table 2.
Univariate analysis of TNBC patient prognosis (n = 214).
| Survival rate (%) |
|||||
|---|---|---|---|---|---|
| Variables | 1 year | 3 years | 5 years | mOS (month) | P-value |
| Age | |||||
| <50 | 99.1 | 96.2 | 88.9 | 77.4 | 0.031a |
| ≥50 | 98.0 | 87.7 | 76.6 | 72.3 | |
| HT | |||||
| IDA | 99.4 | 92.5 | 81.2 | 74.9 | 0.938 |
| MA | 96.6 | 88.2 | 88.2 | 66.6 | |
| TNM stage | |||||
| Ⅰ/Ⅱ | 99.3 | 96.3 | 92.3 | 79.6 | <0.001a |
| Ⅲ/Ⅳ | 98.4 | 83.3 | 63.2 | 66.4 | |
| LM | |||||
| Negative | 99.2 | 95.4 | 89.5 | 78.3 | 0.016a |
| Positive | 98.9 | 88.3 | 74.9 | 72.0 | |
| DM | |||||
| Negative | 98.9 | 94.1 | 90.0 | 78.4 | <0.001a |
| Positive | 100 | 80.3 | 44.6 | 58.8 | |
| Ki67 (%) | |||||
| ≤20 | 100 | 92.0 | 88.0 | 77.1 | 0.484 |
| >20 | 98.6 | 92.5 | 79.6 | 73.7 | |
| MDM2 expresstion | |||||
| Negative | 100 | 96.2 | 91.6 | 79.5 | 0.001a |
| Positive | 98.1 | 87.7 | 66.2 | 63.7 | |
| MDMX expresstion | |||||
| Negative | 99.1 | 98.0 | 90.5 | 79.4 | 0.002a |
| Positive | 99.1 | 85.9 | 74.3 | 71.0 | |
| TAB1 expresstion | |||||
| Negative | 98.1 | 87.5 | 71.7 | 70.2 | 0.006a |
| Positive | 100 | 96.9 | 89.7 | 79.1 | |
Abbreviations: TNBC, triple-negative breast cancer; mOS, median overall survival time; HT, histological type; IDA, invasive ductal carcinoma; MA, medullary carcinoma; LM, lymphatic metastasis; DM, distant metastasis; MDM2, murine double minute 2; MDMX, murine double minute X; TAB1, transforming growth factor β-activated kinase 1-binding protein 1.
a, statistically significant.