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. 2019 Apr 14;20(7):989–998. doi: 10.1080/15384047.2019.1591674

Figure 3.

Figure 3.

Overexpressed miR-202-5p promoted proliferation and inhibited apoptosis of MCF-7 cells in vitro. (a) The result of CCK8 assay reveals that the OD value of MCF-7 cells in different groups. *P < 0.05, compared with miR-NC group. (b) The IC50 value in different groups was tested. **P < 0.01, compared with miR-NC group. ##P < 0.01, compared with Mock group. (c,d) The colony formation assay was performed to examine cell proliferation rate of DOX treating MCF-7 cells. *P < 0.05, **P < 0.01, compared with miR-NC group. (e) The cell proliferation rate was tested by CCK8 assay. **P < 0.01, compared with miR-NC group. (f) Ki67 expression level was examined by immunofluorescence staining. The blue color represented DAPI and the red color represents Ki67 expression (×40). (g,h) The apoptosis rate of MCF-7 cells was detected by flow cytometry. **P < 0.01, compared with miR-NC group.