Table 2. Estimated parameters in probability of use vs. non-use and alcohol use score with nuisance variables on the clinical data (not yet including brain data).
| Intercept | Slope | |||
|---|---|---|---|---|
| Estimate | SE | Estimate | SE | |
| Part 1: Prevalence of alcohol drinking (use vs. non-use)=discrete part of the model | ||||
| Mean | 0.568** | 0.011 | 0.188** | 0.006 |
| Variance | 0.090** | 0.009 | 0.024** | 0.004 |
| Part 2: Alcohol use score of AUDIT = continuous part of the model | ||||
| Mean | 0.693** | 0.037 | 0.498 | 0.642 |
| Variance | 0.618** | 0.087 | 0.218** | 0.046 |
| Regression onto Part two slope | ||||
| Sex | −0.183** | 0.046 | ||
| Age | −0.000 | 0.000 | ||
| TBV | 0.000* | 0.000 | ||
| Site_London | 0.410* | 0.163 | ||
| Site_Nottingham | 0.368* | 0.161 | ||
| Site_Dublin | 0.517* | 0.167 | ||
| Site_Berlin | 0.091 | 0.170 | ||
| Site_Hamburg | 0.122 | 0.162 | ||
| Site_Mannheim | 0.038 | 0.163 | ||
| Site_Paris | 0.079 | 0.163 | ||
| Site_Dresden | −0.044 | 0.163 | ||
| Covariances | ||||
| Covariance between intercept and slope in Part 1 | −0.033** | 0.005 | ||
| Covariance between intercept and slope in Part 2 | −0.078 | 0.050 | ||
| Covariance between the intercepts of Part 1 and Part 2 | 0.124** | 0.012 | ||
*p < 0.05 , **p<0.001, SE = standard error, TBV = total brain volume.