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Silencing of KCNQ1OT1 negatively regulated the migration and EMT progress of CRC cells.
(a) Transwell assays revealed that the migration of CRC cells after KCNQ1OT1 was silenced. (b,c) The mRNA and protein levels of EMT markers (E-cadherin, β-catenin, N-cadherin, Vimentin) were measured by qRT-PCR and western blot assays. (d) Immunofluorescence assays were used to detect the expressions of E-cadherin and N-cadherin. **P < 0.01 vs. control group.
