Table 2.
SLE ≤45 years (n=50) | CARDIA (n=3042) | P value | Women with SLE aged ≤45 years (n=46) | Women in the CARDIA cohort (n=1659) | P value | |
Age, years | 32±8 | 40±4 | < 0.001 | 32±8 | 40±4 | < 0.001 |
Female, n (%) | 46 (92%) | 1659 (54%) | < 0.001 | – | – | – |
Race/ethnicity | ||||||
White, n (%) | 3 (6%) | 1666 (55%) | < 0.001 | 3 (7%) | 859 (52%) | < 0.001 |
Hispanic, n (%) | 16 (32%) | – | – | 14 (30%) | – | – |
Black, n (%) | 24 (48%) | 1376 (45%) | 0.70 | 23 (50%) | 800 (48%) | 0.81 |
Hypertension, n (%) | 22 (44%) | 705 (23%) | < 0.001 | 22 (48%) | 274 (17%) | < 0.001 |
Diabetes, n (%) | 3 (6%) | 305 (10%) | 0.87 | 3 (7%) | 125 (8%) | 0.85 |
Ever smoker, n (%) | 2 (4%) | 1718 (56%) | < 0.001 | 2 (4%) | 884 (53%) | < 0.001 |
BMI, kg/m2 | 27.8±9 | 28.4±6 | 0.49 | 28.2±9 | 28.8±7 | 0.59 |
Total cholesterol, mg/dL | 183±88 | 183±41 | 0.99 | 191±90 | 178±40 | 0.07 |
HDL, mg/dL | 49±19 | 50±16 | 0.69 | 50±19 | 54±16 | 0.10 |
LDL, mg/dL | 100±52 | 111±36 | 0.05 | 106±52 | 107±33 | 0.92 |
Aspirin use, n (%) | 16 (32%) | 213 (7%) | < 0.001 | 14 (30%) | 78 (5%) | < 0.001 |
Characteristics are expressed as n (%) or as the mean±SD. Values in bold are considered significant (∝<0.05).
Data for all patients (left) and women only (right) are shown.
BMI, body mass index; CARDIA, Coronary Artery Risk Development in Young Adults; HDL, high-density lipoprotein; LDL, low-density lipoprotein.