Table 1.

Clinical characteristics of patients with ICI-related thyroid disorders.

Characteristic	Pembro	Nivo	Ipi+ Nivo	Total
Number	18	9	26	53
Age, years
Median (range)	62 (32–82)	60 (42–81)	58 (34–78)	60 (32–82)
Gender, n(%)
Female	10(56)	9(100)	15(58)	34(64)
Male	8(44)	0 (0)	11(42)	19(36)
Malignancy, n(%)
Melanoma	12(67)	3(33)	21(81)	36(68)
Leiomyosarcoma	1(6)	0(0)	0(0)	1(2)
Breast cancer	3(17)	0(0)	0(0)	3(6)
Lung cancer	1(6)	0(0)	0(0)	1(2)
Glioblastoma	1(6)	2(22)	0(0)	3(6)
Renal cell carcinoma	0(0)	0(0)	1(4)	1(2)
Meningioma	0(0)	3(33)	0(0)	3(6)
Bladder cancer	0(0)	1(11)	1(0)	2(4)
Ovarian cancer	0(0)	0(0)	2(0)	2(4)
Malignant neoplasm of esophagus	0(0)	0(0)	1(4)	1(2)
Preexisting thyroid disorder, n(%)
Yes	4(22)	3(33)	1(4)	8(15)
No	14(78)	6(67)	25(96)	45(85)