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. Author manuscript; available in PMC: 2020 Sep 1.
Published in final edited form as: J Psychiatr Res. 2019 Jun 8;116:74–82. doi: 10.1016/j.jpsychires.2019.06.005

Figure 4.

Figure 4.

Mediation analyses showed that thalamic cue activity mediated the correlation between cue-evoked craving and skin conductance response (SCR) in men and women combined (left panels) and in men only (right panels). Thalamic cue activity was computed each of all of the three clusters (ROI_3, A) and the single cluster of the intralaminar/mediodorsal thalamus (ROI_1, B). Mediation analyses were not performed for women as the requirement that X was correlated both with M and Y was not met. The results of mediation for all other models were not significant (Supplementary Tables). The p values of mediation are shown in parentheses. Solid and dotted arrows each represent significant and non-significant correlations. * p < 0.05, ** p < 0.01, *** p < 0.001.