Table 2. Dose requirements (medetomidine for premedication, end-tidal sevoflurane concentration, and medetomidine/dobutamine during maintenance) and the number of horses received a rescue injection of thiopental sodium in 214 Thoroughbred racehorses.
| Group | P-value | ||
|---|---|---|---|
| TG (n=91) | PK (n=123) | ||
| Preanesthetic medetomidine dose (µg/kg) | 6.5 (5–8.5) | 6 (4.8–8) | 0.354 |
| End-tidal sevoflurane concentration (%) | 2.4 ± 0.2 | 2.4 ± 0.2 | 0.578 |
| Medetomidine infusion dose rate (µg/kg/hr)* | 3.0 (0.0–3.0) | 3.0 (0.2–3.0) | <0.001 |
| Dobutamine infusion rate (µg/kg/min)* | 0.67 (0.08–1.56) | 0.43 (0.10–1.40) | <0.001 |
| Number (n) of horses received a rescue injection of thiopental sodium (1.0 g/head) | 4 | 10 | 0.274 |
Results are presented as mean ± standard deviation or median (range). *Significant difference between two groups. For group definitions and doses of induction agents, see Table 1.