Table 8.

Effects of dietary soy isoflavone levels and porcine reproductive and respiratory virus (PRRSV) infection on red blood cell measures in weanling pigs

Item	Uninfected	PRRSV-infected				SEM	P-value
							Uninfected vs. Infected Control	Main effects2		Interaction
	Control1	Control1	Control + ISF1	ETSBM1	ETSBM + ISF1			Soy Source	ISF	Soy Source × ISF
RBC, × 106/µL
0 DPI	6.53	6.66	6.84	6.49	6.81	0.180	0.624	0.456	0.099	0.305
3 DPI	6.20	6.00	6.14	5.90	6.29	0.180	0.419	0.862	0.066	0.234
6 DPI	5.97	6.05	6.17	5.87	6.00	0.175	0.778	0.220	0.375	0.502
14 DPI	5.85	5.31*	5.58	5.25	5.43	0.187	0.050	0.519	0.129	0.436
HGB, g/dL
0 DPI	12.3	11.9	12.5	12.2	12.5	0.341	0.552	0.750	0.190	0.588
3 DPI	11.5	10.6	11.1	10.8	11.4	0.341	0.119	0.472	0.070	0.268
6 DPI	10.9	10.4	10.9	10.5	10.8	0.326	0.386	0.888	0.205	0.633
14 DPI	11.0	9.0*	9.5	9.1	9.5	0.358	0.002	0.874	0.156	0.540
HCT, %
0 DPI	35.1	37.4	39.1	37.9	39.1	0.976	0.294	0.882	0.172	0.591
3 DPI	35.7	33.4	34.9	33.8	35.6	0.976	0.272	0.537	0.081	0.314
6 DPI	34.0	32.9	34.4	33.1	33.7	0.930	0.635	0.722	0.301	0.708
14 DPI	34.7	28.5*	30.3	28.8	30.0	1.03	0.010	0.893	0.116	0.442
MCV, fl
0 DPI	58.6	56.2	57.2	58.5	57.5	1.91	0.281	0.257	0.937	0.579
3 DPI	57.9	55.7	56.9	57.3	56.7	1.75	0.300	0.500	0.801	0.742
6 DPI	57.4	54.6	55.8	56.4	56.1	1.72	0.209	0.346	0.712	0.706
14 DPI	59.6	53.7*	54.2	55.0	55.3	1.79	0.013	0.292	0.700	0.719
MCH, pg
0 DPI	18.6	17.9	18.3	18.8	18.4	0.662	0.331	0.224	0.961	0.498
3 DPI	18.4	17.7	18.1	18.3	18.1	0.650	0.374	0.451	0.698	0.717
6 DPI	18.2	17.3	17.7	17.9	18.0	0.650	0.219	0.283	0.510	0.632
14 DPI	18.8	17.0*	17.1	17.4	17.5	0.675	0.037	0.312	0.775	0.762
MCHC, g/dL
0 DPI	31.8	31.6	32.0	32.0	32.0	0.734	0.721	0.842	0.871	0.988
3 DPI	31.7	31.6b	31.9b	31.9b	29.3a	0.734	0.943	0.092	0.096	0.024
6 DPI	31.7	31.5	31.8	31.6	32.0	0.700	0.561	0.836	0.655	0.968
14 DPI	31.5	31.6	31.6	31.6	31.7	0.774	0.662	0.920	0.991	0.999

*Difference (P ≤ 0.05) between uninfected and infected groups fed the control diet.

^abMeans without common superscript letter differ at P ≤ 0.05.

Values represent least square means of 10 to 12 pigs. All pigs received allotted treatment diet starting −7 DPI. DPI = days post-inoculation; ISF = isoflavones; RBC = red blood cells; HGB = hemoglobin; HCT = packed cell volume; MCV = mean corpuscular volume; MCH = mean corpuscular hemoglobin; MCHC = mean corpuscular hemoglobin concentration.

¹The following diet names have been assigned to a respective experimental diet groups: Control: soy protein concentrate + no supplemented ISF, fed to both uninfected and PRRSV-infected control pigs; Control + ISF: soy protein concentrate + supplemented ISF, fed to PRRSV-infected pigs only; ETSBM: ETSBM + no supplemented ISF, fed to PRRSV-infected pigs only; ETSBM + ISF: ETSBM + supplemented ISF, fed to PRRSV-infected pigs only.

²Main effect of day postinoculation (DPI); no 2- or 3-way interactive effects involving DPI were significant, so they were not included in the statistical model.