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. 2019 Jul 2;9:9533. doi: 10.1038/s41598-019-46042-w

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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(a) Effects of cell aggregate size on the biomass of cell suspension for F. deltoidea var. kunstleri (n = 3). Different size of stainless steel mesh was used to classify cell according to class of sizes. The biggest size of cell aggregate produced the highest dry weight. (b) Effects of cell aggregate size on the flavonoid of cell suspension for F. deltoidea var. kunstleri (n = 3). The flavonoid content produced by the cell was proportionally with the dry weight produced. As the size aggregate of the cells were increased, the flavonoid content of the cells also were increased.