Table 1.
Animal experiments
GSCs | Implanted cell number/mouse | Days after implantation to start treatment | |||||
---|---|---|---|---|---|---|---|
Survival | Western blot | ||||||
Ola | VE822 | Dox | Ola | VE822 | Dox | ||
MGG4-shMYC | 2 × 105 | 12 | — | 9 | — | — | 34 |
BT74-MYC | 1 × 105 | 11 | — | 8 | — | — | 33 |
MGG4-CDK18 | 2 × 105 | 8 | — | 5 | — | — | — |
BT74-shCDK18 | 2 × 105 | 7 | — | 4 | — | — | — |
MGG4 | 2 × 105 | 10 | 9 | — | 35 | 35 | — |
MGG18 | 2 × 105 | 48 | 47 | — | 120 | 120 | — |
GSC glioblastoma stem-like cell, Ola olaparib, Dox doxycycline