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. 2019 Jun 26;9:225. doi: 10.3389/fcimb.2019.00225

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Copyright © 2019 Zhou, Li, Xu, Wang, Bai, Feng, Su, Chen, Wang, Liu, Wang, Zhang and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Different chemotherapy strategies caused changes in the function of the intestinal microbes. (A) PCoA analysis based on KEGG EC (enzyme) abundance (left panel) and top 10 abundance histogram (right panel). (B) PCoA analysis based on CAZy EC abundance (left panel) and top 10 abundance histogram (right panel). (C) KEGG EC top 35 abundance clustering heat map. (D) CAZy EC top 35 abundance clustering heat map. N, negative control; M, model control; CDDP, CDDP chemotherapy; CEH, cepharanthine hydrochloride chemotherapy; Comb, combined chemotherapy strategy.