Table 1.
Body and organ weights.
| VEH (n = 10) | ABX (n = 9) | VEH-FMT (n = 10) | ABX-FMT (n = 10) | One-way ANOVA | VEH vs ABX | VEH-FMT vs ABX-FMT | VEH vs VEH-FMT | ABX vs ABX-FMT | VEH vs ABX-FMT | ABX vs VEH-FMT | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Body mass (g) |
380 ± 23 | 369 ± 22 | 436 ± 27 | 420 ± 24 | <0.0001 | 0.999 | 0.888 | 0.0001 | 0.0002 | 0.004 | 0.0001 |
| RV (mg/100 g) |
58 ± 6 | 51 ± 3 | 55 ± 7 | 61 ± 6 | 0.009 | 0.133 | 0.196 | 0.999 | 0.008 | 0.999 | 0.999 |
| LV (mg/100 g) |
219 ± 14 | 207 ± 10 | 206 ± 14 | 208 ± 9 | 0.053 | – | – | – | – | – | – |
| LV + RV (mg/100 g) |
277 ± 16 | 258 ± 10 | 260 ± 14 | 269 ± 11 | 0.011 | 0.018 | 0.982 | 0.043 | 0.483 | 0.967 | 0.999 |
| Lung dry weight (mg/100 g) |
100 ± 12 | 90 ± 11 | 98 ± 9 | 85 ± 10 | 0.01 | 0.217 | 0.067 | 0.999 | 0.999 | 0.015 | 0.723 |
| Lung wet weight (mg/100 g) |
495 ± 104 | 404 ± 44 | 427 ± 43 | 406 ± 83 | 0.03 | 0.064 | 0.999 | 0.288 | 0.999 | 0.061 | 0.999 |
| Oedema index (% wet weight) |
79 ± 3 | 78 ± 1 | 77 ± 1 | 79 ± 3 | 0.017 | 0.999 | 0.196 | 0.112 | 0.999 | 0.999 | 0.016 |
BW, body weight; RV, right ventricle; LV, left ventricle; VEH, autoclaved deionised water; ABX, antibiotic-treated; VEH-FMT, VEH followed by faecal microbiota transfer; ABX-FMT, antibiotic-treated followed by faecal microbiota transfer. Data are shown as mean ± SD and were statistically compared using one-way ANOVA with Bonferroni post hoc where appropriate, or non-parametric Kruskal-Wallis test with Dunn's post hoc, where appropriate. Each p-value is adjusted to account for multiple comparisons. p-values shown in bold highlight significant differences.