Skip to main content
. 2019 May 15;44:403–418. doi: 10.1016/j.ebiom.2019.05.013

Fig. 4.

Fig. 4

HNF1A regulates the expression of multidrug resistance genes in PDAC cells. (A-B) Quantitative RT-PCR data showing fold changes (2-∆∆CT) in the mRNA expression level of ABCB1, ABCC1, ABCC3 and ABCC5 genes after overexpression of HNF1A in the PANC-1 and MIA PaCa-2 cell lines. (C-D) Western Blot experiments showing the protein levels of the ABCB1, ABCC1, ABCC3 and ABCC5 genes after overexpression of HNF1A in PANC-1 and MIA PaCa-2 cell lines. The graphs shown are representative results of three repeated assays and are presented as mean ± SD. *p < .05, **p < .01 (Student's t-test).