Low levels of HNF1A expression predict chemoresistance in PDAC patients. (A) Representative images of HNF1A staining in PDAC tissues (categorization: low, moderate, and high). (B) The Kaplan–Meier analysis of overall survival stratified by the immunoreactive score of HNF1A expression. (C) Kaplan–Meier analysis of disease-free survival stratified by the immunoreactive score of HNF1A expression. (D–F) The disease-free survival analyses confirmed that the high HNF1A group showed the best survival, the low HNF1A group showed the worst survival, and the moderate HNF1A group showed intermediate disease-free survival. The p-values are shown with the use of the log-rank test (two-sided) **p < .01, ***p < .001 (Kaplan-Meier analysis, log-rank test).