Table 3.
Logistic regression analysis for nocturia in obstructive sleep apnea
| Variable | Univariate analysis regression |
Multivariate analysis regression |
||||||
|---|---|---|---|---|---|---|---|---|
| β | S.E. β | OR (95% CI) | P-value | β | S.E. β | OR (95% CI) | P-value | |
| Clinical | ||||||||
| Age | 0.073 | 0.013 | 1.076 (1.049–1.103) | < 0.001 | 0.050 | 0.017 | 1.052 (1.016–1.088) | 0.004 |
| Male sex | 0.507 | 0.278 | 1.661 (0.962–2.866) | 0.068 | 0.271 | 0.429 | 1.311 (0.565–3.042) | 0.528 |
| HTN | 1.213 | 0.267 | 3.364 (1.993–5.680) | < 0.001 | 0.335 | 0.374 | 1.398 (0.671–2.911) | 0.371 |
| DM | 1.875 | 0.348 | 6.523 (3.296–12.908) | < 0.001 | 1.898 | 0.478 | 6.675 (2.618–17.022) | < 0.001 |
| BMI | 0.017 | 0.028 | 1.017 (0.960–1.077) | 0.571 | ||||
| Neck circumference | -0.002 | 0.034 | 0.998 (0.933–1.067) | 0.948 | ||||
| Waist circumference | 0.012 | 0.011 | 1.012 (0.990–1.035) | 0.296 | ||||
| WHR | 5.728 | 2.276 | 307.416 (3.548–26,635.680) | 0.012 | -2.441 | 3.545 | 0.087 (0.000–90.617) | 0.491 |
| Questionnaire | ||||||||
| ESS | 0.021 | 0.024 | 1.021 (0.973–1.071) | 0.397 | ||||
| PSQI | 0.182 | 0.038 | 1.200 (1.114–1.292) | < 0.001 | 0.234 | 0.051 | 1.264 (1.144–1.397) | < 0.001 |
| Polysomnography | ||||||||
| TST | -0.006 | 0.002 | 0.995 (0.992–0.997) | < 0.001 | -0.004 | 0.002 | 0.996 (0.991–1.001) | 0.081 |
| SE | -0.041 | 0.010 | 0.960 (0.941–0.979) | < 0.001 | -0.031 | 0.017 | 0.969 (0.938–1.001) | 0.059 |
| N3 | -0.197 | 0.074 | 0.821 (0.710–0.949) | 0.008 | -0.100 | 0.079 | 0.905 (0.775–1.056) | 0.206 |
| REM | -0.032 | 0.019 | 0.968 (0.933–1.005) | 0.091 | ||||
| Snoring | -0.011 | 0.006 | 0.990 (0.979–1.000) | 0.057 | 0.001 | 0.008 | 1.001 (0.986–1.017) | 0.910 |
| AI | 0.015 | 0.005 | 1.015 (1.004–1.026) | 0.005 | -0.006 | 0.017 | 0.994 (0.960–1.028) | 0.716 |
| HI | 0.002 | 0.009 | 1.002 (0.985–1.019) | 0.844 | ||||
| AHI | 0.011 | 0.004 | 1.011 (1.002–1.020) | 0.017 | 0.029 | 0.07 | 1.030 (0.898–1.180) | 0.675 |
| Low O2 | -0.027 | 0.011 | 0.973 (0.953–0.994) | 0.011 | 0.047 | 0.028 | 1.048 (0.992–1.107) | 0.094 |
| Mean O2 | -0.223 | 0.057 | 0.800 (0.716–0.894) | < 0.001 | -0.430 | 0.18 | 0.650 (0.457–0.926) | 0.017 |
| T90 | 0.039 | 0.011 | 1.040 (1.018–1.062) | < 0.001 | -0.017 | 0.037 | 0.983 (0.914–1.057) | 0.645 |
| ODI3 | 0.011 | 0.005 | 1.011 (1.002–1.020) | 0.016 | 0.177 | 0.068 | 1.193 (1.044–1.364) | 0.010 |
| ODI4 | 0.014 | 0.005 | 1.014 (1.005–1.023) | 0.004 | 0.128 | 0.052 | 1.136 (1.026–1.258) | 0.014 |
| Arousal index | 0.016 | 0.006 | 1.016 (1.004–1.028) | 0.01 | 0.005 | 0.019 | 1.005 (0.970–1.043) | 0.770 |
S.E., standard error; OR, odds ratio; CI, confidence interval; HTN, hypertension; DM, diabetes mellitus; BMI, body mass index; WHR, waist-hip ratio; ESS, Epworth Sleepiness Scale; PSQI, Pittsburgh Sleep Quality Index; TST, total sleep time; SE, sleep efficacy; REM, rapid eye movement; AI, apnea index; HI, hypopnea index; AHI, apnea-hypopnea index; T90, time spent in desaturation below 90%; ODI3, oxygen desaturation index ≥3%; ODI4, oxygen desaturation index ≥4%.