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. 2019 May 22;20(7):e47563. doi: 10.15252/embr.201847563

Figure EV2. H2Bub1 regulates the expression of a group of ion‐binding proteins.

Figure EV2

  1. mRNA levels of H2Bub1‐affected metal ion‐binding genes in H1299 cells transfected with wild‐type H2B (H2BWT) and K120R‐mutated H2B (H2BK120R) were determined by RT–PCR analysis.
  2. The mRNA levels of the same genes shown in (A) were tested by RT–PCR analysis in H1299 cells transfected with a control siRNA (siCont.) and an RNF20‐specific siRNA (siRNF20).
  3. STRING analysis of the selected metal ion‐binding genes indicated that several metabolism‐related processes are involved, including multiple redox‐related events.