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. 2019 Jun 14;18(2):1922–1930. doi: 10.3892/ol.2019.10480

Figure 2.

Figure 2.

Proliferation, migration and invasion in glioblastoma cell lines with overexpression of miR-181. (A) Expression of miR-181 in U251, A172 and U87 glioblastoma lines was reduced compared with that in NHA cells. (B) Expression of miR-181 in U87 and A172 cells transfected with miR-181 and miR-NC. (C) Proliferation of U87 cells transfected with miR-181 and miR-NC. (D) Proliferation of A172 cells transfected with miR-181 and miR-NC. (E and F) Invasion of U87 and A172 cells transfected with miR-181 and miR-NC. (G and H) Migration of U87 and A172 cells transfected with miR-181 and miR-NC, (magnification ×100). Data are presented as the mean ± standard deviation and based on at least three independent experiments. *P<0.05. miR-181, microRNA-181; miR-NC, miR-negative control; NHA, normal human astrocytes; OD, optical density.