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. 2019 Jun 14;18(2):1840–1846. doi: 10.3892/ol.2019.10483

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Copyright: © Yuan et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — TAMs may promote proliferation of A549 cells. DAPI- and EDU-positive staining indicates the total cells and proliferating cells, respectively (magnification, ×100). Group 1 represents normal control group; group 2 represents THP-1 coculture group; and group 3 represents TAMs coculture group. The EDU proliferation assay test indicated that the proliferation rate of the TAMs coculture group was significantly increased compared with that of the blank control group. ****P<0.0001 vs. control. TAMs, tumor associated macrophages.