Table 1.

Gene ontology terms with significant enrichment for annotated transcripts.

imGPAD -196aKD versusimGPAD-Con		imAPAD -196aKD versusimAPAD-Con		imAPAD -196aKD versusimAPAD-Con: based on transcripts with > 50% fold change and significance p < 0∙01
(n = 441 transcripts)		(n = 22 transcripts)		(n = 47 transcripts)
Gene ontology terms	Enrichment score	Gene ontology terms	Enrichment score	Gene ontology terms	Enrichment score
Extracellular matrix	9∙14	Inflammation and immune response	2∙92	Extracellular region	3∙26
Vasculature development	6∙98	Interleukin 1	1∙85	Hormone, amidation	2∙00
EGF-like region	6∙48	Positive regulation of macromolecule biosynthetic process	1∙76	Extracellular matrix	1∙83
EGF‑calcium binding	5∙36	Acute inflammatory response	1∙74	Cell motility	1∙42
Cell migration	5∙17	Leucine-rich repeat	1∙67	Negative regulation of transcription	1∙41
Insoluble/membrane fraction	4∙59	Angiogenesis	1∙58
Polysaccharide and carbohydrate binding	4∙10
Fibronectin	3∙20
Positive regulation of transcription	3∙05
Regulation of apoptosis	2∙53