Supplementary Fig. 1.

Upregulation of SOX5 is correlated with the patients' prognosis. a, Peak signals detected from the ChIP sequecing revealed that SOX5 might be a potential target of FOX-A1 (The small figure is an enlargement of the first red peak in large plot). b, The GO terms enriched in the subset of most significant candidate genes identified by ChIP-Seq. c, Top 20 enriched pathway. d, SOX5 expression in sensitive and insensitive LAD tissues. ^⁎⁎P < .01. e, The level of SOX5 in paired normal and LAD tissues.^⁎⁎P < .01. f-g, The PFS and OS of LAD patients with high or low level of SOX5 were analyzed by Kaplan-Meier method. ^⁎⁎P < .01. h, Expression correlation between SOX5 and FOX-A1 in LAD tissues. ^⁎⁎P < .01. Data represent the average of three independent experiments (means±standard deviation).