Figure 2.

Effect of PDCD4 overexpression plasmid on the viability of Taxol-treated CRC cells in vitro. CRC cells were divided into four different groups: Empty vector group, PDCD4 overexpression group, Taxol treatment group, and Taxol treatment + PDCD4 overexpression group. Cell viability was examined at 48 h after treatment. Compared with the empty vector group, cell viability in the PDCD4 overexpression and Taxol treatment groups was significantly reduced, and further reduced by co-administration of Taxol and the PDCD4 plasmid. Data are presented as the means ± SD of three independent experiments. *P<0.05, **P<0.01. PDCS4, programmed cell death factor 4; CRC, colorectal cancer.