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. 2019 May 27;18(2):1402–1408. doi: 10.3892/ol.2019.10398

Figure 5.

Figure 5.

Relative mRNA expression of Bax, Bcl-2, and MMP-9. Relative mRNA expression of Bax, Bcl-2 and MMP-9 was analyzed using RT-qPCR. Results were normalized to GAPDH and expressed relative to the empty vector group levels that were assigned a value of 1. Compared with the empty vector group, Bax mRNA levels in the PDCD4 overexpression and Taxol treatment groups were significantly increased, and further induced by co-administration of Taxol and the PDCD4 plasmid. Bcl-2 and MMP-9 mRNA levels were significantly decreased in the PDCD4 overexpression and Taxol groups, and enhanced by co-administration of Taxol and the PDCD4 plasmid. Data are presented as the means ± SD of three independent experiments. *P<0.05, **P<0.01, ***P<0.001. PDCS4, programmed cell death factor 4; CRC, colorectal cancer; Bcl-2, B-cell lymphoma-2; BAX, Bcl-2-associated X protein; MMP-9, matrix metalloproteinase-9.