Figure 1.
Sensitivity of epithelial ovarian cancer cells to cisplatin treatment. (A) SKOV3 and SKOV3/DDP cells were treated with various concentrations of cisplatin for 48 h, and the cell viability was determined using a Cell Counting Kit-8. The dose response curves presented as a sigmoidal shape. (B) The IC50 values of cisplatin in SKOV3 and SKOV3/DDP cells were calculated. Each value represents the mean ± standard deviation from three independent experiments. *P<0.05. IC50, half maximal inhibitory concentration.