Prediction of targets of the upregulated miRNAs. (A) Clustering analysis of the predicted targets of 11 abnormally expressed miRNAs by four databases including TargetScan, miRWALK, miRDB and starbase. (B) Analysis of the expression patterns of the 605 target mRNAs in GC using the TCGA database. (C) A network between the targets and differentially expressed miRNAs was constructed using Cytoscape. Green nodes, upregulated miRNAs; red nodes, target mRNAs of upregulated miRNAs; yellow nodes, downregulated miRNAs; purple nodes, target mRNAs of downregulated miRNAs. TCGA, The Cancer Genome Atlas; miRNA or miR, microRNA.