Table I.
Associations between miR-125b expression and the clinical features of patients with melanoma.
Clinical features | Number, n (%) | miR-125b expression (mean ± standard deviation) | P-value |
---|---|---|---|
Sex | 0.443 | ||
Male | 13 (44.83) | 0.30±0.18 | |
Female | 16 (55.17) | 0.38±0.32 | |
Age, years | 0.874 | ||
≥60 | 15 (51.72) | 0.35±0.27 | |
<60 | 14 (48.28) | 0.34±0.27 | |
Tumor diameter, cm | 0.425 | ||
≥2 | 11 (37.93) | 0.29±0.29 | |
<2 | 18 (62.07) | 0.38±0.26 | |
Lymph node metastasis | 0.001a | ||
No | 16 (55.17) | 0.46±0.31 | |
Yes | 13 (44.83) | 0.21±0.11 | |
TNM stage | 0.004a | ||
I/II | 15 (51.72) | 0.47±0.31 | |
III/IV | 14 (48.28) | 0.21±0.09 | |
Lesion location | 0.991 | ||
Acral | 17 (58.62) | 0.35±0.25 | |
Non-acral | 12 (41.38) | 0.35±0.30 |
A t-test was used to compare the differences among groups.
P<0.01. miR-125, microRNA-125b.