Table II.
Kyoto Encyclopedia of Genes and Genomes pathway analysis of differentially expressed genes.
| Terma | Genes | P-value |
|---|---|---|
| hsa04064: NF-κB signaling pathway | ICAM1, TNF, BCL2A1, LTA | 0.001 |
| hsa05205: Proteoglycans in cancer | TNF, MMP9, ITGA2, MMP2, FN1 | 0.001 |
| hsa04512: ECM-receptor interaction | ITGA1, ITGA2, COL11A1, FN1 | 0.001 |
| hsa04668: TNF signaling pathway | ICAM1, TNF, MMP9, LTA | 0.002 |
| hsa04670: Leukocyte transendothelial migration | ICAM1, MMP9, PECAM1, MMP2 | 0.002 |
| hsa04514: Cell adhesion molecules (CAMs) | ICAM1, SELL, PECAM1, VCAN | 0.004 |
| hsa05219: Bladder cancer | MMP9, MMP2, MMP1 | 0.004 |
| hsa05144: Malaria | ICAM1, TNF, PECAM1 | 0.006 |
| hsa05200: Pathways in cancer | MMP9, ITGA2, MMP2, MMP1, FN1 | 0.011 |
| hsa04510: Focal adhesion | ITGA1, ITGA2, COL11A1, FN1 | 0.011 |
| hsa05410: Hypertrophic cardiomyopathy (HCM) | TNF, ITGA1, ITGA2 | 0.014 |
| hsa04060: Cytokine-cytokine receptor interaction | TNF, CD27, LTA, TNFSF8 | 0.015 |
| hsa05414: Dilated cardiomyopathy | TNF, ITGA1, ITGA2 | 0.016 |
| hsa04640: Hematopoietic cell lineage | TNF, ITGA1, ITGA2 | 0.016 |
| hsa05323: Rheumatoid arthritis | ICAM1, TNF, MMP1 | 0.017 |
| hsa05146: Amoebiasis | TNF, COL11A1, FN1 | 0.024 |
| hsa04151: PI3K-Akt signaling pathway | ITGA1, ITGA2, COL11A1, FN1 | 0.043 |
a
Pathway terms with P<0.05 were considered statistically significant.