Table I.
Metabolism-related molecules | Comparison between different ssubtypes | Refs. |
---|---|---|
GLUT1 | ATC > PTC > FTC > FA | (19,21) |
HK2 | PTC with BRAFV600E > PTC without BRAFV600E | (19) |
Other subtypes > MTC | ||
PKM | ||
PKM2 mRNA | BCPAP and TPC1 > NC | (33) |
PK activity: | BCPAP > TPC1 | |
LDH-A | ATC > PTC and FTC > NC | (37) |
Serine/glycine | PDTC and PTC > MTC | (38) |
Metabolism-related proteins | PTC > FTC | |
PTC with BRAFV600E > PTC without BRAFV600E | ||
Glutamine metabolism-related proteins | (39) | |
Tumor and Stroma | ATC > other subtypes | |
GLS1 and GDH | ||
Tumor ASCT2 | MTC > FTC | |
Tumor GLS1 and GDH | ATC > PTC > FTC > FA | |
PTC with BRAFV600E > PTC without BRAFV600E | ||
TOMM20 | ATC > NC | (9,14) |
PTC > NC | ||
MCT1 | ATC > NC | (9) |
PTC < NC |