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A 62 year old acutely encephalopathic female with acute toxic leukoencephalopathy (ATL), who had been administered fludarabine 3 weeks prior to imaging for treatment of multiple myeloma. She expired 19 days after MRI. 1A-C: there was bilateral, symmetric PVWM hyperintensity (arrows) on FLAIR (A), with reduced diffusion on DWI (B) and on ADC map (C).
