Fig. 9.

A 37 year old male with alcohol abuse presented with visual changes, who was ultimately diagnosed with ATL from Marchiafava-Bignami disease. 9A-C: On the initial MRI, reduced diffusion is noted in the body (dotted arrows) and the splenium (arrows) of the corpus callosum on DWI MRI (A) and ADC map (B), while these same areas are hyperintense on FLAIR (C). On a follow up MRI 2 months later, subsequent focal atrophy was present within the callosal splenium (arrows), having elevated diffusion that appears dark on DWI (D) that is less visible on SWI (E); focal atrophy is also noted within the callosal body (dotted arrow) on sagittal FLAIR (F).