TABLE 5.

Multivariate Analysis of Overall, Disease-Specific, and Local Recurrence–Free Survival in Patients With T1–2N0 Disease and Close\Positive Margins According to Adjuvant Radiotherapy (n = 208)

		Overall Survival		Disease-Specific Survival		Local Recurrence–Free Survival
Variable	No.	HR (95% CI)	P	HR (95% CI)	P	HR (95% CI)	P
Sex					.051		.33
Male	136			1		1
Female	72			1.56 (0.99–2.43)		0.7 (0.34–1.4)
Missing	0
Age							.11
<70 y	157					1
≥70 y	51					1.88 (0.87–3.79)
Missing	0
Treatment			.0094		.02		.24
Surgery	130	1		1		1
S+PORT	78	0.58 (0.38–0.88)		0.56 (0.33–0.92)		0.71 (0.38–1.26)
Missing	0
DOI							.02
<4 mm	32					1
≥4 mm	125					2.54 (1.16–6.7)
Missing	51
pT
1	76
2	132
Missing	0

Abbreviations: CI, confidence interval; DOI, depth of invasion; HR, hazard ratio; pT, pathological T stage; S+PORT, surgery and postoperative radiation therapy.

Patients who received adjuvant treatment other than radiation were excluded from the analysis.