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. 2019 Jul 2;2(4):e201900443. doi: 10.26508/lsa.201900443

Figure S7. Comparison of bNMF clustering applied to a PBMC mixture without and with imputation of RNA counts.

Figure S7.

A mixture of seven immune cell types (monocytes, B cells, CD34+ HSCs, helper T cells [Th], natural killer [NK] cells, cytotoxic T lymphocytes [CTL], and Treg; n = 100 each; see Fig 4F) was used. (A) Evidence profiles. (B, C) tSNE maps (derived from raw count matrix, (B); derived from imputed count matrix, (C); colored by cell types of origin [left column] and by cluster assignment from H matrix [right column; rank 7]). Note that Th and Treg cells are grouped together in cluster 4. (D) Cell counts in each cluster.