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. 2019 Jul 3;11:59. doi: 10.1186/s13195-019-0511-2

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — LC axonal degeneration in 11-month-old rats infused with htauE14 at 2–3 months old. a–c LC cell counts in htauE14 and control rats. (N: htau/GFP/non-infused: 7/6/6). d–f NET fibers (red) in the piriform cortex (PC) (N: htau/GFP/non-infused: 6/6/5). g–i DBH fibers (red) in the PC. (N: htau/GFP/non-infused: 6/5/5). j–l β1-adrenoceptors in the PC. (N: htau/GFP: 4/4). m–o Iba-1 in the PC. (N: htau/GFP/non-infused: 6/5/6). LOT, lateral olfactory tract. Scale bars, 50 μm