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Induction of a senescence (A) siRNA2-loaded chitosan coated polylactic-co-glycolic acid (PLGA) nanoparticle-treated cells; (B) Naked siRNA2-treated cells; (C) Blank nanoparticle-treated cells; (D) Untreated cells from a separate inhibition experiment were stained for β-galactosidase activity at pH 6.
