TABLE 1.
Respiratory mechanical parameters obtained at baseline (BL) and following lung injury (T0) in the rabbits ventilated with physiological variable ventilation (PVV), mathematically variable ventilation (MVV), pressure-controlled mode (PCV), and pressure controlled mode with regular sighs (PCS).
|
MP groups |
HP groups |
||||||||||
| PVV | MVV | PCV | PCS | PVV | MVV | PCV | PCS | ||||
| Raw (cmH2O.s/l) | BL | PEEP 6 | 9.2 (7.3-11.1) | 8.6 (6.7-10.5) | 8.4 (7.5-9.2) | 9.2 (6.0-12.3) | PEEP 6 | 9.2 (8.2-10.3) | 8.7 (7.1-10.3) | 8.3 (7.4-9.3) | 8.7 (7.2-10.2) |
| T0 | PEEP 6 | 14.5* (12.6-16.4) | 12.3* (9.7-14.8) | 12.0* (9.5-14.5) | 12.0* (8.3-15.6) | PEEP 9 | 11.1 (8.2-14.0) | 10.4 (8.4-12.4) | 10.7* (9.9-11.6) | 11.5* (9.3-13.8) | |
| G (cmH2O/l) | BL | PEEP 6 | 80.2 (67.4-93.1) | 87.3 (77.0-97.5) | 91.0 (76.2-105.8) | 82.3 (65.0-99.6) | PEEP 6 | 76.8 (63.6-90.0) | 86.2 (73.4-99.1) | 88.9 (74.9-102.8) | 91.1 (78.9-103.3) |
| T0 | PEEP 6 | 251* (153-350) | 309* (192-426) | 348* (170-527) | 262* (142-383) | PEEP 9 | 177* (128-226) | 207*# (144-269) | 174*# (123-225) | 196* (146-247) | |
| H (cmH2O/l) | BL | PEEP 6 | 252 (220-286) | 269 (233-305) | 267 (235-299) | 257 (243-271) | PEEP 6 | 246 (230-262) | 255 (217-292) | 274 (237-311) | 277 (247-306) |
| T0 | PEEP 6 | 1105* (594-1616) | 1162* (629-1695) | 1438* (817-2059) | 1149* (513-1785) | PEEP 9 | 856* (453-1259) | 790* (504-1076) | 875*# (649-1101) | 948* (607-1289) | |
Raw, airway resistance; G, tissue damping; H, tissue elastance. Values displayed as group mean (95% confidence interval). *p < 0.05 vs. BL, #p < 0.05 vs. PEEP 6.